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Functional recovery of glycine receptors in spastic murine model of startle disease

✍ Scribed by Annamaria Molon; Simone Di Giovanni; Yetrib Hathout; JoAnne Natale; Eric P. Hoffman


Book ID
113811869
Publisher
Elsevier Science
Year
2006
Tongue
English
Weight
739 KB
Volume
21
Category
Article
ISSN
0969-9961

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## Abstract Huntington disease (HD) is an autosomal dominant disorder in which degeneration of medium‐sized spiny striatal neurons occurs. The HD gene and the protein it encodes, huntingtin, have been identified but their functions remain unknown. Transgenic mouse models for HD have been developed