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Functional reconstitution of an active recombinant human chymase from Pichia pastoris cell lysate

โœ Scribed by Hiroshi Nakakubo; Masanori Morita; Teruaki Imada; Shinji Takai; Naotaka Shiota; Mizuo Miyazaki; Norifumi Nakamura


Publisher
John Wiley and Sons
Year
2000
Tongue
English
Weight
161 KB
Volume
16
Category
Article
ISSN
0749-503X

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๐Ÿ“œ SIMILAR VOLUMES


Secretory production of recombinant huma
โœ Hiroshi Nakakubo; Hajime Fukuyama; Masahide Nakajima; Teruaki Imada; Shusei Uno; ๐Ÿ“‚ Article ๐Ÿ“… 2000 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 140 KB ๐Ÿ‘ 1 views

We succeeded in expressing in a Pichia pastoris (P. pastoris) host a cDNA encoding a mature human chymase (h-chymase) which was secreted directly into the culture medium. Recombinant human heart chymase (rh-chymase) was purified from the culture medium via a single one-step heparin-agarose column ch