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Functional polymorphisms in SOCS1 and PTPN22 genes correlate with the response to imatinib treatment in newly diagnosed chronic-phase chronic myeloid leukemia

✍ Scribed by Vicent Guillem; Paula Amat; Francisco Cervantes; Alberto Alvarez-Larrán; Jose Cervera; Margherita Maffioli; Beatriz Bellosillo; María Collado; Isabel Marugán; Francisco Martínez-Ruiz; Juan-Carlos Hernández-Boluda


Book ID
113773478
Publisher
Elsevier Science
Year
2012
Tongue
English
Weight
337 KB
Volume
36
Category
Article
ISSN
0145-2126

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✍ Yesid Alvarado; Hagop Kantarjian; Susan O'Brien; Stefan Faderl; Gautam Borthakur 📂 Article 📅 2009 🏛 John Wiley and Sons 🌐 English ⚖ 338 KB 👁 2 views

## Abstract ## BACKGROUND: The European LeukemiaNet recommendations for chronic myeloid leukemia (CML) defined a group of patients with suboptimal response to imatinib. The significance of this response was not well defined. ## METHODS: The significance of having had a suboptimal response during

Imatinib dose escalation in two patients