Functional polymorphism of cytotoxic T-lymphocyte antigen 4 and nasopharyngeal carcinoma susceptibility in a Chinese population
β Scribed by M. Xiao; F. Qi; X. Chen; Z. Luo; L. Zhang; C. Zheng; S. Hu; X. Jiang; M. Zhou; J. Tang
- Book ID
- 114831641
- Publisher
- John Wiley and Sons
- Year
- 2010
- Tongue
- English
- Weight
- 83 KB
- Volume
- 37
- Category
- Article
- ISSN
- 1744-3121
No coin nor oath required. For personal study only.
π SIMILAR VOLUMES
## Abstract ## BACKGROUND: Polymorphisms in the cytotoxic Tβlymphocyte antigen 4 (__CTLAβ4__) gene have been implicated in susceptibility to cancer, but the many published studies have reported inconclusive results. The objective of the current study was to conduct a metaβanalysis investigating th
The CTLA-4 gene encodes a T-cell receptor that is involved in the regulation of T-cell activation. Recent studies have demonstrated an association of a microsatellite polymorphism [variant lengths of a dinucleotide (AT)n repeat] lying in exon 3 of the CTLA-4 gene, specifically a 106-bp allele, with