✦ LIBER ✦

Functional polymorphism in ALOX15 results in increased allele-specific transcription in macrophages through binding of the transcription factor SPI1

✍ Scribed by Jonas Wittwer; Jacqueline Marti-Jaun; Martin Hersberger

Publisher: John Wiley and Sons
Year: 2006
Tongue: English
Weight: 88 KB
Volume: 27
Category: Article
ISSN: 1059-7794
DOI: 10.1002/humu.20328

No coin nor oath required. For personal study only.

📜 SIMILAR VOLUMES

Functional polymorphism in ALOX15 result

Functional polymorphism in ALOX15 results in increased allele-specific transcription in macrophages through binding of the transcription factor SPI1

✍ Jonas Wittwer; Jacqueline Marti-Jaun; Martin Hersberger 📂 Article 📅 2006 🏛 John Wiley and Sons 🌐 English ⚖ 274 KB

## Communicated by Stephen Chanock The reticulocyte-type 15-lipoxygenase-1 (ALOX15) has antiinflammatory and inflammatory effects, and is implicated in the development of asthma, arthritis, and atherosclerosis. We screened the human ALOX15 gene for variations because genetic variability in ALOX15

The functional −443T/C osteopontin promo

The functional −443T/C osteopontin promoter polymorphism influences osteopontin gene expression in melanoma cells via binding of c-Myb transcription factor

✍ Julia Schultz; Peter Lorenz; Saleh M. Ibrahim; Günther Kundt; Gerd Gross; Manfre 📂 Article 📅 2009 🏛 John Wiley and Sons 🌐 English ⚖ 261 KB

## Abstract In the present report, the possible role of a recently described functional polymorphism of the osteopontin (OPN) promoter at position −443 (−443T/C) for OPN expression in melanoma cells was addressed. As shown by __real‐time__ PCR analysis, melanoma metastases that were homozygous for