Low density lipoprotein receptor (LDLR)
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Jian Wang; Erin Huff; Lenny Janecka; Robert A. Hegele
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Article
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2001
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John Wiley and Sons
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English
⚖ 20 KB
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Heterozygous familial hypercholesterolemia (FH) is a relatively common autosomal dominant disorder, which is characterized by elevated plasma concentrations of low density lipoprotein (LDL) cholesterol and early coronary heart disease. FH results from mutations in the gene encoding the LDL receptor