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Functional MRI of Basal Ganglia Responsiveness to Levodopa in Parkinsonian Rhesus Monkeys

✍ Scribed by Qun Chen; Anders H. Andersen; Zhiming Zhang; Aliza Ovadia; Wayne A. Cass; Don M. Gash; Malcolm J. Avison

Book ID
115606988
Publisher
Elsevier Science
Year
1999
Tongue
English
Weight
275 KB
Volume
158
Category
Article
ISSN
0014-4886

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## Abstract Homeostatic interactions between dopamine and glutamate are central to the normal physiology of the basal ganglia. This relationship is altered in Parkinsonism and in levodopa‐induced dyskinesias (LID), resulting in an upregulation of corticostriatal glutamatergic function. Kynurenic ac