Functional localization of a melanoma tumor suppressor gene to a small (2 Mb) region on 11q23
✍ Scribed by Robertson, Gavin P; Goldberg, Eleonora K; Lugo, Tracy G; Fountain, Jane W
- Book ID
- 110062098
- Publisher
- Nature Publishing Group
- Year
- 1999
- Tongue
- English
- Weight
- 200 KB
- Volume
- 18
- Category
- Article
- ISSN
- 0950-9232
No coin nor oath required. For personal study only.
📜 SIMILAR VOLUMES
Uterine leiomyoma is a benign smooth muscle tumor of the myometrium and is the most commonly encountered neoplasm in women of reproductive age. As for most benign tumors, the pathogenesis of leiomyoma remains obscure, especially at the molecular genetic level. The purpose of this study was to perfor
Human prostate cancers frequently show loss of heterozygosity at loci on the short arm of chromosome 8. In order t o take a step toward isolation of the putative tumor suppressor gene(s) on 8p via positional cloning, we performed high-resolution deletion mapping in 46 prostate cancers (stage B, 20 c
To identify the location of one or more putative tumor suppressor genes that may be involved in urinary bladder cancer, we examined 82 such tumors for allelic losses at 19 microsatellite loci on 8p. Loss of heterozygosity was observed in 31 of the cases. Deletion mapping identified a commonly delete
The human histone H2A.X gene is unusual in that its transcripts are alternatively processed to yield two species, one a 0.6-kb replication-linked histone mRNA and the other a 1.6-kb polyadenylated mRNA. The H2A.X gene has been localized by fluorescence in situ hybridization to chromosome 11q23.2-q23