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Functional Interaction of Erythropoietin and Stem Cell Factor Receptors is Essential for Erythroid Colony Formation

✍ Scribed by Hong Wu, Ursula Klingmüller, Adriana Acurio, Jonathan G. Hsiao and Harvey F. Lodish

Book ID
123640462
Publisher
National Academy of Sciences
Year
1997
Tongue
English
Weight
714 KB
Volume
94
Category
Article
ISSN
0027-8424

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To clarify the manner by which erythropoietin (EP), stem cell factor (SCF), or insulin-like growth factor I (IGF-I) regulate erythropoiesis, apoptosis of human erythroid progenitor cells was investigated. Human burst-forming units-erythroid (BFU-E) partially purified from peripheral blood were cultu