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Functional inhibition of endogenously produced urokinase decreases cell proliferation in a human melanoma cell line

✍ Scribed by Kirchhelmer, Johannes C.; Wojta, Johann; Christ, Gunter; Binder, Bernd R.


Book ID
122822342
Publisher
Elsevier Science
Year
1989
Tongue
English
Weight
345 KB
Volume
3
Category
Article
ISSN
0268-9499

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Expression of urokinase-type plasminogen activator (u-PA) strongly correlates with a malignant tumor cell phenotype. In the multistep process of metastasis, different cellular functions are influenced by urokinase. The enzyme is known to be effective via both proteolytical and signal transduction me