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Functional inactivation of NF2/merlin in human mesothelioma

✍ Scribed by Thurneysen, Claudio; Opitz, Isabelle; Kurtz, Stefanie; Weder, Walter; Stahel, Rolf A.; Felley-Bosco, Emanuela


Book ID
119320016
Publisher
Elsevier Science
Year
2009
Tongue
English
Weight
604 KB
Volume
64
Category
Article
ISSN
0169-5002

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We previously reported NF2 mutations in malignant mesothelioma (MM) cell lines and corresponding primary tumors. We have now generated polyclonal antibodies that specifically recognize the C-terminus of the NF2 protein. Western blot analysis was performed on 25 MM cell lines, 14 of which showed no N