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Functional haplotypes in citrullinating enzyme peptidylarginine deiminase 4 are associated with rheumatoid arthritis

✍ Scribed by K Yamamoto, A Suzuki, X Chang, S Tokuhiro, T Sawada, Y Nakamura…

Book ID
120708137
Publisher
BioMed Central
Year
2003
Tongue
English
Weight
554 KB
Volume
5
Category
Article
ISSN
1478-6354

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## Abstract ## Objective Anti–cyclic citrullinated peptide (anti‐CCP) antibodies are rheumatoid arthritis (RA)–specific serologic markers. RA susceptibility has been associated with HLA–DRB1 shared epitope (SE) alleles and single‐nucleotide polymorphism (SNP) haplotypes in the peptidyl arginine de