Functional Genomics: Methods and Protocols (Methods in Molecular Biology, Vol. 224)

✍ Scribed by Michael J. Brownstein (editor), Arkady Khodursky (editor)

Publisher: Humana
Year: 2003
Tongue: English
Leaves: 264
Category: Library

No coin nor oath required. For personal study only.

✦ Synopsis

This collection of robust, readily reproducible methods for microarray-based studies includes expert guidance in the optimal data analysis and informatics. On the methods side are proven techniques for monitoring subcellular RNA localization en masse, for mapping chromosomes at the resolution of a single gene, and for surveying the steady-state genome-wide distribution of DNA binding proteins in vivo. For those workers dealing with massive data sets, the book discusses the methodological aspects of data analysis and informatics in the design of microarray experiments, the choice of test statistic, and the assessment of observational significance, data reduction, and clustering.

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