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Functional genome screen for therapeutic targets of osteosarcoma

โœ Scribed by Umio Yamaguchi; Kazufumi Honda; Reiko Satow; Eisuke Kobayashi; Robert Nakayama; Hitoshi Ichikawa; Ayako Shoji; Miki Shitashige; Mari Masuda; Akira Kawai; Hirokazu Chuman; Yukihide Iwamoto; Setsuo Hirohashi; Tesshi Yamada

Book ID
108586496
Publisher
John Wiley and Sons
Year
2009
Tongue
English
Weight
1016 KB
Volume
100
Category
Article
ISSN
1347-9032

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## Abstract Genes that are highly overexpressed in tumor cells can be required for tumor cell survival and have the potential to be selective therapeutic targets. In an attempt to identify such targets, we combined a functional genomics and a systems biology approach to assess the consequences of R