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Functional genetic variation at the NRGN gene and schizophrenia: Evidence from a gene-based case–control study and gene expression analysis

✍ Scribed by Kazutaka Ohi; Ryota Hashimoto; Yuka Yasuda; Motoyuki Fukumoto; Hidenaga Yamamori; Satomi Umeda-Yano; Takeya Okada; Kouzin Kamino; Takashi Morihara; Masao Iwase; Hiroaki Kazui; Shusuke Numata; Masashi Ikeda; Tohru Ohnuma; Nakao Iwata; Shu-ichi Ueno; Norio Ozaki; Tetsuro Ohmori; Heii Arai; Masatoshi Takeda


Book ID
111995339
Publisher
John Wiley and Sons
Year
2012
Tongue
English
Weight
261 KB
Volume
159B
Category
Article
ISSN
1552-4841

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## Abstract Increasing evidence has supported the hypothesis of a neurodevelopmental component in the etiology of schizophrenia. Recently, several independent microarray gene expression studies have revealed downregulated expression of myelin‐related genes in the postmortem brains of schizophrenia