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Functional genetic polymorphisms in SIM2 and ETS2: Role in Down syndrome


Book ID
123476577
Publisher
Elsevier Science
Year
2012
Tongue
English
Weight
77 KB
Volume
30
Category
Article
ISSN
0736-5748

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Identification of chromosome 21 DNA poly
✍ G. Camp; H. Backhovens; M. Cruts; A. Wehnert; W. Hul; P. Stinissen; C. Broeckhov πŸ“‚ Article πŸ“… 1991 πŸ› Springer 🌐 English βš– 542 KB

Linkage studies in families with presenile onset of Alzheimer's disease (AD) indicated the presence of a predisposing gene on the proximal long arm of chromosome 21. We mapped four new loci in the candidate AD region using somatic cell hybrids. For three of the four loci, several restriction fragmen