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Functional effect of metabotropic glutamate and GABA receptors on Insulin Secretion

โœ Scribed by Nicola L Brice; Elek Molnar; Stephen J.H Ashcroft


Book ID
117370060
Publisher
Elsevier Science
Year
2000
Tongue
English
Weight
148 KB
Volume
50
Category
Article
ISSN
0168-8227

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Cultured human melanocytes express mGlu5 metabotropic glutamate (mGlu) receptors, as shown by RT-PCR, immunocytochemistry, Western blot analysis, and measurement of agonist-stimulated polyphosphoinositide hydrolysis. The mGlu5 receptor agonists (S)-3,5-dihydroxyphenylglycine and quisqualate increase