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Functional dynamics of H3K9 methylation during meiotic prophase progression

✍ Scribed by Tachibana, Makoto; Nozaki, Masami; Takeda, Naoki; Shinkai, Yoichi

Book ID
110032138
Publisher
Nature Publishing Group
Year
2007
Tongue
English
Weight
809 KB
Volume
26
Category
Article
ISSN
0261-4189

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## Background In the mouse zygote the paternal genome undergoes dramatic structural and epigenetic changes. Chromosomes are decondensed, protamines replaced by histones and DNA is rapidly and actively demethylated. The epigenetic asymmetry between parental genomes remains at least until the 2-cell