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Functional domains of GABAA receptors

✍ Scribed by Geoffrey B. Smith; Richard W. Olsen

Book ID
117340838
Publisher
Elsevier Science
Year
1995
Tongue
English
Weight
994 KB
Volume
16
Category
Article
ISSN
0165-6147

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✍ B. Birnir; M.L. Tierney; M. Lim; G.B. Cox; P.W. Gage πŸ“‚ Article πŸ“… 1997 πŸ› John Wiley and Sons 🌐 English βš– 50 KB πŸ‘ 1 views

The effects on the functional properties of the a 1 b 1 GABA A receptor when the 58 (a 1 Val260; b 1 Ile255) hydrophobic amino acids in the second transmembrane (M2) region were changed to threonine were examined. In response to a saturating concentration of GABA, the current evoked in mutant recept