Functional Diversity of Vertebrate ARNT Proteins: Identification of ARNT2 as the Predominant Form of ARNT in the Marine Teleost,Fundulus heteroclitus

Identification and functional characteri

Identification and functional characterization of hypoxia-inducible factor 2? from the estuarine teleost,Fundulus heteroclitus: Interaction of HIF-2? with two ARNT2 splice variants

✍ Powell, Wade H. ;Hahn, Mark E. 📂 Article 📅 2002 🏛 John Wiley and Sons 🌐 English ⚖ 573 KB

## Abstract The hypoxia‐inducible factors (HIFs) are dimeric transcription factors that mediate changes in gene expression during adaptation of animals to oxygen stress. Both alpha (HIFα) and beta (ARNT) subunits are members of the basic helix‐loop‐helix/Per‐ARNT‐Sim family of proteins. Mammals hav