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Functional differences in steroid sulfate uptake of organic anion transporter 4 (OAT4) and organic anion transporting polypeptide 2B1 (OATP2B1) in human placenta

✍ Scribed by Bernhard Ugele; Andrew Bahn; Monika Rex-Haffner


Book ID
116698199
Publisher
Elsevier Science
Year
2008
Tongue
English
Weight
629 KB
Volume
111
Category
Article
ISSN
0960-0760

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Organic anion–transporting polypeptide 1
✍ IvΓ‘n L. Csanaky; Hong Lu; Youcai Zhang; Kenichiro Ogura; Supratim Choudhuri; Cur πŸ“‚ Article πŸ“… 2010 πŸ› John Wiley and Sons 🌐 English βš– 713 KB

The organic anion-transporting polypeptide 1b family (Oatp1b2 in rodents and OATP1B1/1B3 in humans) is liver-specific and transports various chemicals into the liver. However, the role of the Oatp1b family in the hepatic uptake of bile acids (BAs) into the liver is unknown. Therefore, in Oatp1b2-nul