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Functional deficiencies of spleen dendritic cells in autoimmune MRL/lpr mice

โœ Scribed by Akira Ito; Hee J. Woo; Yasuyuki Imai; Toshiaki Osawa

Book ID
107906148
Publisher
Elsevier Science
Year
1988
Tongue
English
Weight
381 KB
Volume
17
Category
Article
ISSN
0165-2478

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## Abstract ## Objective To determine whether innate receptor signals play an important role in the development of autoimmune nephritis in MRL/__lpr__ mice, an experimental model of lupus nephritis. ## Methods MyD88 is a critical adaptor that is involved in signaling pathways through all of the