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Functional control of gastrin releasing peptide (GRP) mRNA in rat stomach

✍ Scribed by R. Dimaline; A.K. Sandvik; G. Barclay; G.J. Dockray

Book ID
115925954
Publisher
Elsevier Science
Year
1992
Tongue
English
Weight
294 KB
Volume
301
Category
Article
ISSN
0014-5793

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Gastrin-releasing peptide (GRP) receptors are present in pancreatic islets, though their regulation is unknown except for homologous desensitization. The modulation of binding of GRP to mouse pancreatic islets and INS-1 cells was studied. At 60 min (steady-state), total binding of [ 125 I-Tyr 15 ] G