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Functional contributions of synaptically localized NR2B subunits of the NMDA receptor to synaptic transmission and long-term potentiation in the adult mouse CNS

✍ Scribed by Hideki Miwa; Masahiro Fukaya; Ayako M. Watabe; Masahiko Watanabe; Toshiya Manabe

Book ID: 110115990
Publisher: Cambridge University Press
Year: 2008
Tongue: English
Weight: 554 KB
Volume: 586
Category: Article
ISSN: 0022-3751
DOI: 10.1113/jphysiol.2007.147652

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## Abstract It has recently been proposed that activation of the NR2A subunit results in Long‐term potentiation (LTP) induction, whereas activation of the NR2B subunit results in long‐term depression (LTD) induction. The present study undertakes to replicate these findings in vivo to determine if a