Functional cloning and reconstitution of vertebrate odorant receptors
โ Scribed by Kazushige Touhara
- Book ID
- 117172873
- Publisher
- Elsevier Science
- Year
- 2001
- Tongue
- English
- Weight
- 218 KB
- Volume
- 68
- Category
- Article
- ISSN
- 0024-3205
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## Vertebrate odorant receptor (OR) genes have been isolated and characterized in several taxa, including bony fish and mammals. However, the search for more ancient vertebrate OR genes has been unsuccessful to date, indicating that these ancient genes share little sequence identity with previousl
Odorant receptors (ORs) located in the nasal epithelium, at the ciliated surface of olfactory sensory neurons, represent the initial step of a transduction cascade that leads to odor detection. ORs form the largest and most diverse family of G-protein-coupled receptors (GPCRs). They are encoded by a