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Functional characterization of the rat multispecific organic anion transporter OAT1 mediating basolateral uptake of anionic drugs in the kidney

✍ Scribed by Yuichi Uwai; Masahiro Okuda; Kenji Takami; Yukiya Hashimoto; Ken-ichi Inui


Book ID
117109956
Publisher
Elsevier Science
Year
1998
Tongue
English
Weight
139 KB
Volume
438
Category
Article
ISSN
0014-5793

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To characterize the transport functions of a recently cloned basolateral organic anion transporting polypeptide of rat hepatocytes we performed further kinetic transport and substrate cis-inhibition studies in organic anion-transporting polypeptide-cRNA injected Xenopus Zaevis oocytes. The studies d