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Functional characterization of NADP-dependent isocitrate dehydrogenase isozymes from Trypanosoma cruzi

✍ Scribed by Alejandro E. Leroux; Dante A. Maugeri; Juan J. Cazzulo; Cristina Nowicki


Book ID
113803412
Publisher
Elsevier Science
Year
2011
Tongue
English
Weight
314 KB
Volume
177
Category
Article
ISSN
0166-6851

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We have characterized biochemical effects of Idh ~m in Drosophila melanogaster. This is a "'null"-activity allele for NADP+-dependent isocitrate dehydrogenase (NADP-IDH) isolated from a natural population. The homozygous mutant strain has 5% of the NADP-IDH specific activity found in controls and le