Functional Characterization of Murine CD25 Expressing B Cells
β Scribed by S. Amu; I. Gjertsson; M. Brisslert
- Book ID
- 110861895
- Publisher
- John Wiley and Sons
- Year
- 2010
- Tongue
- English
- Weight
- 256 KB
- Volume
- 71
- Category
- Article
- ISSN
- 0300-9475
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Co-stimulatory signals mediated by the interaction of B7-1/B7-2 with CD28 are important for the activation of CD4 + T cells stimulated with antigen on antigen-presenting cells. There are controversies about the expression and function of B7-1/B7-2 on CD4 + T cells. The aim of this study was to analy
## Abstract To evaluate the __in vivo__ effect of immunosuppressive glucocorticoids on CD4^+^CD25^+^ T regulatory cells, we injected dexamethasone (Dex) into BALB/c mice. Administrationof Dex enhanced the proportion of CD4^+^CD25^+^ cells and the ratio of CD4^+^CD25^+^ cells to CD4^+^CD25^β^ cells