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Functional characterization of human and cynomolgus monkey UDP-glucuronosyltransferase 1A6 enzymes

✍ Scribed by Nobumitsu Hanioka; Yuri Takeda; Hideto Jinno; Toshiko Tanaka-Kagawa; Shinsaku Naito; Akiko Koeda; Takefumi Shimizu; Mamoru Nomura; Shizuo Narimatsu


Book ID
113517445
Publisher
Elsevier Science
Year
2006
Tongue
English
Weight
427 KB
Volume
164
Category
Article
ISSN
0009-2797

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✍ Ryoichi Fujiwara; Miki Nakajima; Shingo Oda; Hiroyuki Yamanaka; Shin-ichi Ikushi πŸ“‚ Article πŸ“… 2010 πŸ› John Wiley and Sons 🌐 English βš– 314 KB

Glucuronidation catalyzed by UDP-glucuronosyltransferase (UGT) enzymes is an important pathway in the metabolism of drugs as well as environmental chemicals. In this study, protein-protein interactions between human UGT2B7 and UGT1As and their effects on the enzymatic activities were investigated us