Functional Characterization of Cultured Cells Derived from an Intraepidermal Carcinoma of the Skin (IEC-1)
โ Scribed by Anthony J. Dicker; Magdalena M. Serewko; Alison L. Dahler; Kum Kum Khanna; Pritinder Kaur; Amy Li; Geoff M. Strutton; Nicholas A. Saunders
- Book ID
- 115603741
- Publisher
- Elsevier Science
- Year
- 2000
- Tongue
- English
- Weight
- 304 KB
- Volume
- 258
- Category
- Article
- ISSN
- 0014-4827
No coin nor oath required. For personal study only.
๐ SIMILAR VOLUMES
## Abstract The primary neuroendocrine carcinoma of the skin or Merkel cell carcinoma (MCC) is a skin tumor with aggressive biological behaviour. Experimental models for investigating the biological properties of the tumor are prerequisite for developing new therapeutic approaches. In this study, w
Loss of wild-type p53, either through deletion or mutation, has been demonstrated in most squamous cell carcinomas of the head and neck (HNSCC). Whether these mutant molecules contribute to tumor progression purely through loss of wild-type functions or by growth-promoting mechanisms, however, remai