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Functional characterization and role of INrf2 in antioxidant response element-mediated expression and antioxidant induction of NAD(P)H:quinone oxidoreductase1 gene

โœ Scribed by Dhakshinamoorthy, Saravanakumar; Jaiswal, Anil K

Book ID
110064779
Publisher
Nature Publishing Group
Year
2001
Tongue
English
Weight
398 KB
Volume
20
Category
Article
ISSN
0950-9232

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NAD(P)H:quinone oxidoreductase (QR) and glutathione-S-transferases (GSTs) are among the enzymes believed to protect an organism against oxidative stress. To test if redox-cycling compounds regulate the expression of these enzymes in cells of neural origin, primary cultures of rat cerebellar neurons