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Functional CD40 ligand (CD40L) is expressed on cultured murine epidermal langerhans cells

✍ Scribed by Nakamura, Koichiro; Salgado, Claudio Guedes; Asahima, Akihiko; Irie, Shinkichi; Koyama, Yoh-ichi; Tamaki, Kunihiko

Book ID
121983121
Publisher
Elsevier Science
Year
1998
Tongue
English
Weight
173 KB
Volume
16
Category
Article
ISSN
0923-1811

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Langerhans cells (LC) are professional antigen-presenting cells of dendritic cell (DC) lineage and are critical for the induction of primary immune responses in skin. Following antigenic stimulation, LC migrate to regional lymph nodes and induce antigen-specific activation of T cells. After primary