Functional assessment of sciatic nerve reconstruction: Biodegradable poly (DLLA-ϵ-CL) nerve guides versus autologous nerve grafts
✍ Scribed by Marcel F. Meek; Jeroen R. Dijkstra; Wilfred F.A. Den Dunnen; Jos Ijkema-Paassen; Jeff M. Schakenraad; Albert Gramsbergen; Peter H. Robinson
- Publisher
- John Wiley and Sons
- Year
- 1999
- Tongue
- English
- Weight
- 212 KB
- Volume
- 19
- Category
- Article
- ISSN
- 0738-1085
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## Abstract The aim of this study was to compare functional peripheral nerve recovery in the rat sciatic nerve model after reconstruction of a 10‐mm gap with a biodegradable poly (DLLA‐ϵ‐CL) nerve guide, as filled with either fresh skeletal muscle or phosphate‐buffered saline (PBS). During 24 weeks
## Abstract Previous morphological and morphometrical studies showed that fresh‐skeletal‐muscle‐enriched vein segments are good conduits for leading peripheral nerve regeneration. In the present study, we investigated the morphological features of peripheral nerve fibers regenerated along a 10‐mm‐l
This study was performed to evaluate the long-term functional nerve recovery after reconstruction of a 10-mm gap in the sciatic nerve of the rat, with a thin-walled nerve guide, composed of a biodegradable copolymer of DL-lactide and -caprolactone [p(DLLA--CL)]. To evaluate both motor and sensory ne