## Abstract The miR‐34 family members are direct transcriptional targets of tumor suppressor p53, and loss of miR‐34 function can impair p53‐mediated cell cycle arrest and apoptosis. A potentially functional SNP rs4938723 (T > C) was found in the promoter region of __pri‐miR‐34b/c__ (423 bp from th
✦ LIBER ✦
Functional assessment of a promoter polymorphism in S100B, a putative risk variant for bipolar disorder
✍ Scribed by Elif Dagdan; Derek W. Morris; Matthew Campbell; Matthew Hill; Matthias Rothermundt; Florian Kästner; Christa Hohoff; Christof von Eiff; Petra Krakowitzky; Michael Gill; Patrick McKeon; Siobhan Roche
- Publisher
- John Wiley and Sons
- Year
- 2011
- Tongue
- English
- Weight
- 284 KB
- Volume
- 156
- Category
- Article
- ISSN
- 1552-4841
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It has been suggested that the serotonin transporter (5-hydroxytryptamine-transporter or 5-HTT) may be involved in the pathogenesis of affective disorders. Recently, Collier et al. (1996) found that the frequency of the low-activity short variant (s) of the 5-HTT-linked polymorphic region (5-HTTLPR)