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Functional aspects of the tumor necrosis factor gene family in pregnancy

โœ Scribed by J.S. Hunt


Book ID
117315499
Publisher
Elsevier Science
Year
1996
Tongue
English
Weight
160 KB
Volume
17
Category
Article
ISSN
0143-4004

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โœ Mark D. Crew; Mark E. Filipowsky ๐Ÿ“‚ Article ๐Ÿ“… 1992 ๐Ÿ› Springer-Verlag ๐ŸŒ English โš– 315 KB

Tumor necrosis factor/cachectin (TNF) is a potent pleiotropic cytokine implicated in a number of pathological conditions including septic shock and cachexia (Beutler and Cerami 1986;Beutler 1990). In mice and humans, TNF is synthesized by activated monocytes mainly as a 26 kd propeptide which is pro