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Functional Anchoring of the cAMP-Dependent Protein Kinase

✍ Scribed by Brian J Murphy; John D Scott


Book ID
114342269
Publisher
Elsevier Science
Year
1998
Tongue
English
Weight
935 KB
Volume
8
Category
Article
ISSN
1050-1738

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The CAMP-dependent protein kinase (cAK) from Diciyosteliurn discoideurn is an enzyme composed of one catalytic and one regulatory subunit. Upon binding of CAMP, the holoenzyme dissociates to liberate free active catalytic subunits. The cAK is developmentally regulated, ranging from very little activ