Functional analysis of theDrosophila CDC2 Dm gene in fission yeast
✍ Scribed by Bejarano, E. R. ;Muñoz, M. J. ;Jimenez, J.
- Publisher
- Springer
- Year
- 1995
- Tongue
- English
- Weight
- 944 KB
- Volume
- 248
- Category
- Article
- ISSN
- 0026-8925
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A DNA fragment called suc1 has been found to rescue cells mutated in the cell cycle control gene cdc2 of the fission yeast Schizosaccharomyces pombe. The suppressing activity of suc1 is observed when it is present on a multicopy number plasmid. The gene does not hybridize to cdc2 and maps elsewhere
One possible route to the evaluation of gene function is a quantitative approach based on the concepts of metabolic control analysis (MCA). An important first step in such an analysis is to determine the effect of deleting individual genes on the growth rate (or fitness) of S. cerevisiae. Since the