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Functional analysis of the Lactococcus lactis usp45 secretion signal in the secretion of a homologous proteinase and a heterologous α-amylase

✍ Scribed by van Asseldonk, Martien ;de Vos, Willem M. ;Simons, Guus


Publisher
Springer
Year
1993
Tongue
English
Weight
1005 KB
Volume
240
Category
Article
ISSN
0026-8925

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We report the identification and functional analysis of the first missense ADAMTS10 mutation (c.73G4A; p.Ala25Thr) causing recessive Weill-Marchesani syndrome (WMS). The Ala25 residue affected by the missense mutation is at the À1 position relative to the ADAMTS10 signal peptidase cleavage site. p.A