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Functional analysis of primers and templates in the synthesis of DNA catalyzed by human immunodeficiency virus type 1 reverse transcriptase

✍ Scribed by Georgyi A. NEVINSKY; Marie-Line ANDREOLA; Vitalyi I. JAMKOVOY; Asja S. LEVINA; Philip J. BARR; Laura TARRAGO-LITVAK; Danièle THARAUD; Simon LITVAK


Book ID
115129423
Publisher
John Wiley and Sons
Year
1992
Tongue
English
Weight
848 KB
Volume
207
Category
Article
ISSN
1432-1327

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The conformation of the DNA and the interactions of the nucleic acid with the protein in a complex of human immunodeficiency virus type 1 (HIV-1) reverse transcriptase (RT) and a 19-mer/18-mer double-stranded DNA template-primer (dsDNA) are described. The structure of this HIV-1 RT complex with dsDN