Cholinergic and GABAergic neurons in the medial septum/ vertical limb of the diagonal band of Broca (MS/vDB) projecting to the hippocampus, constitute the septohippocampal projection, which is important for hippocampal-dependent learning and memory. There is also evidence for an extrinsic as well as
Functional Abnormalities in the Hippocampus and Impaired Hippocampal-dependent Learning in Mice Lacking the 5HT1A Receptors
β Scribed by Zoltan Sarnyai; Etienne L. Sibille; Constantine Pavlides; Robert J. Fenster; Bruce S. McEwen; Miklos Toth
- Book ID
- 109105554
- Publisher
- John Wiley and Sons
- Year
- 2006
- Tongue
- English
- Weight
- 6 KB
- Volume
- 6
- Category
- Article
- ISSN
- 1080-563X
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## Abstract P revious behavioral studies (Minichiello et al., Neuron 1999;24:401β414) showed that mice deficient for the TrkB receptor in the forebrain were unable to learn a swimming navigation task with an invisible platform and were severely impaired in finding a visible platform in the same set