Function of dendritic cells and changes in T cell proliferation in antigen-induced nonresponsiveness
β Scribed by S. Hill; A. Stackpoole; I. Kimber; S.C. Knight
- Book ID
- 113134912
- Publisher
- Elsevier Science
- Year
- 1992
- Tongue
- English
- Weight
- 650 KB
- Volume
- 139
- Category
- Article
- ISSN
- 0008-8749
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Dendritic cells (DCs) are "professional" antigen-presenting cells capable of stimulating T-cell proliferation and cytotoxicity when loaded with and presenting specific antigens, including tumor antigens. We demonstrated the stimulation of an autologous cytotoxic T-cell response elicited by DC loaded
## Abstract B cells could be stimulated to proliferate by mitomycin Cβtreated normal T cells that were activated by rabbit antiβmouse brain antiserum (RaMBr). The B cell proliferation peaked 48 h after the initiation of the cultures. The T cell subset involved was Lytβ1^+^, 2^β^. The B and T cells