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Function of B-cell antigen receptor of different classes

✍ Scribed by Kwang-Myong Kim; Michael Reth

Publisher
Elsevier Science
Year
1995
Tongue
English
Weight
578 KB
Volume
44
Category
Article
ISSN
0165-2478

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The binding of antigens to the B cell antigen receptor (BCR) results in the initiation of signaling cascades and the internalization of the antigens for processing and presentation. Recent studies indicate that antigen binding destabilizes the BCR as a mechanism to down-regulate B cell responses. Tw