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Function and structure of recombinant single chain calcineurin

✍ Scribed by Yun-Long Qin; Da-Yu Yu; Qun Wei


Book ID
117054364
Publisher
Elsevier Science
Year
2003
Tongue
English
Weight
190 KB
Volume
308
Category
Article
ISSN
0006-291X

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Calcineurin (CN), a Ca 2+ /calmodulin (CaM)-dependent serine/threonine protein phosphatase, is a heterodimer composed of a catalytic subunit (CNA) and a regulatory subunit (CNB). The activity of CNA is under the control of two functionally distinct, but structurally similar Ca 2+ -regulated proteins