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Fumonisin B1 and the kidney: Modes of action for renal tumor formation by fumonisin B1 in rodents

✍ Scribed by Müller, Stephanie; Dekant, Wolfgang; Mally, Angela

Book ID
118441798
Publisher
Elsevier Science
Year
2012
Tongue
English
Weight
742 KB
Volume
50
Category
Article
ISSN
0278-6915

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✍ Angela Mally; Wolfgang Dekant 📂 Article 📅 2009 🏛 John Wiley and Sons 🌐 English ⚖ 843 KB

## Abstract The mycotoxin ochratoxin A (OTA) is a potent renal carcinogen in rodents. OTA is only slowly eliminated due to high affinity to plasma proteins and inefficient biotransformation. A number of mechanisms have been proposed to account for renal tumor formation. DNA adduct formation, mainly