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Fumaric acid esters

โœ Scribed by Martin Rostami Yazdi; Ulrich Mrowietz


Book ID
116368483
Publisher
Elsevier Science
Year
2008
Tongue
English
Weight
218 KB
Volume
26
Category
Article
ISSN
0738-081X

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## Background Psoriasis is a chronic inflammatory skin disease that can be successfully treated with a mixture of fumaric acid esters (FAE) formulated as enteric-coated tablets for oral use. These tablets consist of dimethylfumarate (DMF) and salts of monoethylfumarate (MEF) and its main bioactive

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x4C-labelled samples of diethyl-, ethyl n-hexyl-and di-n-hexyl fumarates have been used in studies at 60 ~ of their radical copolymerizations with styrene and with vinyl acetate. Changing the diluent from benzene to dimethylformamide in some of the copolymerizatious had no effect on the compositions