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Fulminant Rickettsia tsutsugamushi infection associated with haemophagocytic syndrome

✍ Scribed by Hiromichi Iwasaki; Kenzo Hashimoto; Nobuhiro Takada; Takashi Nakayama; Takanori Ueda; Toru Nakamura


Book ID
118556376
Publisher
The Lancet
Year
1994
Tongue
English
Weight
168 KB
Volume
343
Category
Article
ISSN
0140-6736

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## Abstract Haemophagocytic syndrome (HPS) or haemophagocytic lymphohistiocytosis (HLH) is a rare disease caused by a dysfunction of cytotoxic T cells and NK cells. This T cell/NK cell dysregulation causes an aberrant cytokine release, resulting in proliferation/activation of histiocytes with subse