Fulminant leukemic polyradiculoneuropathy in a case of B-cell prolymphocytic leukemia. A clinicopathologic report

✍ Scribed by Catherine Haberland; Mary Cipriani; Omer Kucuk; Gunseli Sarpel; Ediz Z. Ezdinli; Jae O. Ro

• Book ID: 102672828
• Publisher: John Wiley and Sons
• Year: 1987
• Tongue: English
• Weight: 795 KB
• Volume: 60
• Category: Article
• ISSN: 0008-543X
• DOI: 10.1002/1097-0142(19871001)60:7<1454::aid-cncr2820600708>3.0.co;2-j

✦ Synopsis

A 52 year old man with a 10-month history of &cell prolymphocytic leukemia (PLL) died of an apparent acute fulminant polyradiculoneuropathy, a condition generally attributed to paraneoplastic complication. The pathologic examination disclosed diffuse leukemic infiltrations of the peripheral nervous system. It is suggested that this particularly aggressive form of B-cell chronic prolymphocytic leukemia presented a constellation of features that promoted the invasion of the peripheral nervous system by way of the bloodstream and may explain the unusual clinical presentation.