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Fulminant lactic acidosis in two patients with Type 2 diabetes treated with metformin

✍ Scribed by R. Brassøe; T. Elkmann; M. Hempel; C. H. Gravholt

Book ID: 110924566
Publisher: John Wiley and Sons
Year: 2005
Tongue: English
Weight: 65 KB
Volume: 22
Category: Article
ISSN: 0742-3071
DOI: 10.1111/j.1464-5491.2005.01650.x

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## Background: The plasma cell differentiation antigen (pc-1) is an inhibitor of insulin receptor tyrosine kinase activity, and has been implicated in the pathogenesis of insulin resistance in type 2 diabetes. metformin increases peripheral insulin sensitivity and, therefore, we have studied the ef