Propylthiouracil is a commonly used medication for hyperthyroidism. Though propylthiouracil-induced hepatotoxicity is a rarely encountered problem, death due to fulminant hepatic failure may occur. In the English literature, only 34 cases have been described with severe hepatotoxicity secondary to t
Fulminant hepatic failure associated with the use of black cohosh: A case report
โ Scribed by Christopher R. Lynch; Milan E. Folkers; William R. Hutson
- Publisher
- John Wiley and Sons
- Year
- 2006
- Tongue
- English
- Weight
- 304 KB
- Volume
- 12
- Category
- Article
- ISSN
- 1527-6465
- DOI
- 10.1002/lt.20778
No coin nor oath required. For personal study only.
โฆ Synopsis
With data from the Women's Health Initiative indicating that estrogen plus progesterone are associated with an increased risk of cardiovascular events, many patients and practitioners are looking for alternative therapies to manage menopausal symptoms. One alternative is black cohosh, an herbal product used primarily to treat these symptoms. In recent years there have been several case reports associating this substance with hepatitis and fulminant hepatic failure. We present a case of a woman who developed hepatic failure requiring liver transplantation from the use of this herb.
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