Fulminant demyelinating neuropathy mimicking cerebral death

✍ Scribed by Nandini Bakshi; Ricardo A. Maselli; Sidney M. Gospe Jr; William G. Ellis; Craig McDonald; Raul N. Mandler

• Book ID: 101249420
• Publisher: John Wiley and Sons
• Year: 1997
• Tongue: English
• Weight: 154 KB
• Volume: 20
• Category: Article
• ISSN: 0148-639X
• DOI: 10.1002/(sici)1097-4598(199712)20:12<1595::aid-mus17>3.0.co;2-#

✦ Synopsis

Guillain-Barré syndrome can very rarely present with acute quadripares and cranial nerve involvement resembling a locked-in state. We describe a very unusual case of fulminant neuropathy in a child who was previously exposed to vincristine. The clinical picture resembled brain death; however, electrodiagnostic studies led to the diagnosis of a peripheral neuropathy. Serial electrodiagnostic studies and pathologic findings confirmed demyelination.